Controlled Clin Trials Urol by Louis Denis Download PDF EPUB FB2
Read the latest articles of Controlled Clinical Trials atElsevier’s leading platform of peer-reviewed scholarly literature.
Vol Issue 5 Pages (October ) Vol Issue 4 Pages (August ) Vol Issue 3 Pages (June ). Homma Y, Kawabe K. Health-related quality of life of Japanese patients with overactive bladder treated with extended-release tolterodine or immediate-release oxybutynin: a randomized, placebo-controlled trial.
World J Urol. Oct; 22 (4)–6. [PubMed: ]Author: Bradley P Carlin, Hwanhee Hong, Tatyana A Shamliyan, François Sainfort, Robert L Kane. "This book succeeds admirably in this aim and is accessible to a wide audience, including clinical investigators, statisticians, and those involved in data management and the administration of clinical trials." —Controlled Clinical Trials "This book is an outstanding practical guide to the design, planning, execution Controlled Clin Trials Urol book analysis of clinical Cited by: Urinary retention: benefit of gradual bladder decompression - myth or truth.
A randomized controlled trial Urol Int. ;91(2) doi: / Epub Jul Authors S Boettcher 1, A S Brandt, S Roth, M J Mathers, D A Lazica. Affiliation 1 Department of Cited by: 8. Urol Clin N Am View Abstract Shore N, A Review of the Prostatic Urethral Lift for Lower Urinary Tract Symptoms: Symptom Relief, Flow Improvement, and Preservation of Sexual Function in Men With Benign Prostatic Hyperplasia.
Contemporary Clinical Trials is an international peer reviewed journal that publishes manuscripts pertaining to all aspects of clinical trials, including, but not limited to, design, conduct, analysis, regulation and ethics. Manuscripts submitted should appeal to a readership drawn from disciplines including medicine, biostatistics.
Casodex, a new nonsteroidal antiandrogen, is presently being investigated in phase III studies as a new hormonal treatment for advanced prostatic cancer. The safety and efficacy of Casodex at a dosage of 50 mg. daily for 24 weeks in patients with benign prostatic hypertrophy were investigated in this double-blind placebo-controlled trial.
Purpose Retrospective studies suggest that metastasis-directed therapy (MDT) for oligorecurrent prostate cancer (PCa) improves progression-free survival. We aimed to assess the benefit of MDT in a randomized phase II trial.
Patients and Methods In this multicenter, randomized, phase II study, patients with asymptomatic PCa were eligible if they had had a biochemical recurrence after primary.
CiteScore: ℹ CiteScore: CiteScore measures the average citations received per peer-reviewed document published in this title. CiteScore values are based on citation counts in a range of four years (e.g.
) to peer-reviewed documents (articles, reviews, conference papers, data papers and book chapters) published in the same four calendar years, divided by the number of.
investig clin urol • March 7, Evaluation of pain and catheter-related bladder discomfort relative to balloon volumes of indwelling urinary catheters: A prospective study. investig clin urol •. These results are consistent with those from another large placebo-controlled clinical trial of onabotulinumtoxinA in OAB patients with UI, which showed a mean decrease from baseline in UI episodes per day of − at wk 12 following treatment with onabotulinumtoxinA U, in line with the mean decrease of − observed in the present.
PURPOSE Enzalutamide, a potent androgen-receptor inhibitor, has demonstrated significant benefits in metastatic and nonmetastatic castration-resistant prostate cancer. We evaluated the efficacy and safety of enzalutamide in metastatic hormone-sensitive prostate cancer (mHSPC).
METHODS ARCHES ( identifier: NCT) is a multinational, double-blind, phase III trial, wherein. Reply to Satoshi Funada, Takashi Yoshioka, and Luo Yan's Letter to the Editor re: Guohua Zeng, Chao Cai, Xianzhong Duan, et al.
Mini Percutaneous Nephrolithotomy Is a Noninferior Modality to Standard Percutaneous Nephrolithotomy for the Management of 20–40 mm Renal Calculi: A Multicenter Randomized Controlled Trial. Eur Urol. Raloxifene to prevent gonadotropin-releasing hormone agonist-induced bone loss in men with prostate cancer: a randomized controlled trial.
J Clin Endocrinol Metab ; Crossref; Web. Chemohormonal Therapy in Metastatic Hormone-Sensitive Prostate Cancer: Long-Term Survival Analysis of the Randomized Phase III E CHAARTED Trial J Clin Oncol. Apr 10;36(11) doi: /JCO World J Urol.
;29(1) Kumar AS, Kelleher DC, Sigle GW. Bowel preparation before elective surgery. Clin Colon Rectal Surg. ;26(3) Adamina M, Kehlet H, Tomlinson GA, et al.
Enhanced recovery pathways optimize health outcomes and resource utilization: a meta-analysis of randomized controlled trials in colorectal surgery.
All trials were randomized (Sipuleucel-T or control), double-blinded, placebo-controlled and multi-centric.
The primary endpoint was TTP in two studies (14,15) and OS in one study (16) (Table-2). Patients were randomly assigned in a ratio to receive either Sipuleucel-T or placebo every 2 weeks, for a total of three infusions.
Ther Adv Urol. ; Oelke M, Giulano F, Mirone V, et al. Monotherapy with tadalafil or tamsulosin similarly improved lower urinary tract symptoms suggestive of benign prostatic hyperplasia in an international, randomized, parallel, placebo-controlled clinical trial.
Eur Urol. ; The combination of abiraterone acetate plus prednisone with ADT was associated with significantly longer overall survival than placebos plus ADT in men with newly diagnosed high-risk mCSPC and had a manageable safety profile.
These findings support the use of abiraterone acetate plus prednisone as a standard of care in patients with high-risk mCSPC. The immune hypothesis led to two randomized controlled trials published in from the Southwest Oncology Group Results of a randomized phase III trial.
J Clin OncolLink, An analysis of the ASSURE (ECOG-ACRIN ) adjuvant trial. J UrolCrossref. Most of the studies performed semi-rigid URS with laser as energy source (17, 19–22), although pneumatic lithotripsy was done in two studies (17, 18).
LU was performed through retroperitoneal access in 3 studies (19, 20, 22), transperitoneal access in 2 studies (17, 21), or both in 1 study.
Background: Urinary tract infections (UTIs) are common among women and frequently recur. Depletion of vaginal lactobacilli is associated with UTI risk, which suggests that repletion may be beneficial. We conducted a double-blind placebo-controlled trial of a Lactobacillus crispatus intravaginal suppository probiotic (Lactin-V; Osel) for prevention of recurrent UTI in premenopausal women.
Prostate cancer is the most common cancer in older men in the United States (USA) and Western Europe. Androgen deprivation (AD) constitutes, in most cases, the first-line of treatment for these cases. The negative impact of CAD in quality of life, secondary to the adverse events of sustained hormone deprivation, plus the costs of this therapy, motivated the intermittent treatment approach.
For the first review question, randomised controlled trials (RCTs) examining parenteral oestrogen in patients diagnosed with prostate cancer were included.
Studies had to report at least one of the following outcome measures: overall survival, disease-free survival, disease progression, adverse events, quality of life, and economic costs.
The Medical Therapy of Prostatic Symptoms (MTOPS) is a clinical research study sponsored by the National Institutes of Health (NIH). The study will test whether the oral drugs finasteride (Proscar) and doxazosin (Cardura), alone or together, can delay or prevent further worsening of symptoms in men with Benign Prostatic Hyperplasia (BPH).
These 3 controlled studies show significant reduction in disease progression with the use of intravesical BCG. Overall, the mean rate of progression is reduced from 28% in control subjects to 14% in those receiving BCG.
BCG immunotherapy reduced tumor recurrence by an average of 40%, compared with the 14% average reduction with chemotherapy.
written metaphor and story can be used to increase knowledge of the biology of pain and reduce pain-related catastrophizing.
Methods: In this randomized single-blind partial cross-over controlled trial, 79 people with chronic pain received either a booklet of metaphors and stories conveying key pain biology concepts or a booklet containing advice on how to manage chronic pain.
RCT, randomized controlled trial; MIBC, muscle-invasive bladder cancer. The information for the included studies is presented in Tables 1 and and2 2 [ 14, 15, 18, 26 ].
All included trials were prospective RCTs. Materials and methods: Cochrane Central Register of Controlled Trials, MEDLINE®, EMBASE®, Scopus and Web of Science® were searched for sporadic renal tumors that were surgically treated with partial or radical nephrectomy. Generic inverse variance with fixed effects models were used to determine the pooled HR for each outcome.
randomized, dose ranging trial. J Urol. ;– This Peters KM, Carrico DJ, Perez-Marrero RA, Khan AU, Wooldridge randomized controlled trial has been cited as the landmark study LS, Davis GL, et al.
Randomized trial of percutaneous tibial nerve on dosing of BoNT/A for idiopathic overactive bladder.Racial and ethnic minorities in the US suffer disproportionately from obesity and associated co-morbidities. Yet the clinical trial literature lacks sufficient attention to these populations .Indeed, 86% of weight management studies between and failed to even report the race/ethnicity of recruited participants .Successful “reach” to minority populations—with adequate.Prostate cancer is very common, affecting about one in nine men during their lifetime, but most do not die or develop complications.
The ProtecT trial randomised men with prostate-specific antigen-detected localised prostate cancer to active monitoring (AM), radical prostatectomy, or radiotherapy, and followed them up for 10yr.
We found that >90 out of every men with localised prostate.